N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine

N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine

BOS-172722

CAS: 1578245-44-9

Molecular Formula: C24H30N8O

N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine - Names and Identifiers

Name	BOS-172722
Synonyms	BOS-172722 N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine Pyrido[3,4-d]pyrimidine-2,8-diamine, N8-(2,2-dimethylpropyl)-N2-[2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl]-6-methyl-
CAS	1578245-44-9

N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine - Physico-chemical Properties

Molecular Formula	C24H30N8O
Molar Mass	446.55
Density	1.25±0.1 g/cm3(Predicted)
Boling Point	672.2±65.0 °C(Predicted)
pKa	5.83±0.30(Predicted)
Storage Condition	2-8℃
Use	BOS-172722 is a unipolar spindle 1 (MPS1) checkpoint inhibitor with an IC50 value of 2 nM.

N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine - Reference Information

introduction

BOS-172722 is an inhibitor of unipolar spindle 1(MPS1) checkpoint, IC50 is 2 nM. BOS-172722 also has potential in treating various forms of breast cancer.

Last Update：2024-04-09 20:52:54

N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine

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N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine
N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
1029512-07-9

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